Apitoxin Apitel


"The most powerful anti-inflammatory pain-killer of nature"

apitherapy apitel
Apitoxin Producers
Pioneers in Apitherap


Apitoxin Bee protein cream (BEE VENOM CREAM) Apitoxin 100 for healt Apitoxin 100 for beauty


Apitoxin apitel is produced by an acid secretion gland and an alkaline secretion gland included in the inner part of the bee’s abdomen. Through a crystallization process, Apitoxinapitel looses the traces of nitrogenous fats responsible of the sharp pain produced by the sting of a bee.



The active components of the Apitoxinapitel not only work locally, but also they intervene in the hormonal system stimulating and regulating the levels of cortisone produced by the organism itself. It expands the blood vessels of brain, has an hypotensor effect and stimulates the development of diverse defense reflexes.
- Inflammations of traumatic origin, tendinitis (including “athlete’s elbow”), sharp hematoma, contusions, edemas, feints, ligaments distensions, contractures, muscles splits, sport lesions.

- Rheumatic affections: Polyarthritis, osteoarthritis, Rheumatoid arthritis, arthrosis.

- Fibermalgia.

- Multiple sclerosis.

- Autoinmune deseases.

- Cronic pain.

- Herpes Zoster, and genital herpes (It efficiently helps reducing pain).

- Varixes, varicose ulcers. Reduction of arterial pressure.

- Treatment of chronic pain. Inflammation of sciatic, facial nerves, intercostal neuralgias.

- In the case of those patients who are allergic to bee sting, this product is extremely useful to reduce pain as a result of the progressive production of inmuneglobulin.

- Cellulitis treatment: The Bee Protein cream with bee venom works, through the action of Hyaluronidase, attacking the polymers of hyaluronic acid reducing the viscosity of intracellular fluid. It also helps activating local blood stream which increases the possibility to dilute fatty nodules.


PEPTIDES: 50-60%
Melitine: Composed of 26 aminoacids, representing 40 to 60 % of the macromolecules of Apitoxinapitel. It easily crosses the brain blood barrier stimulating the secretion of ACTH by pituitary gland which is related to the adrenal gland responsible of cortisone production in the body. Its pharmacological activity has been specified as: bactericidal, antifungous, inhibitor of central nervous system, radioprotector, vasodilating and anti-inflammatory. It obstructs calcium and potassium channels, provoking a powerful analgesic action.

MCDP (MAST CELL DEGRANULATING PEPTIDE): It constitutes 2% of the peptides, also called Peptide 401 and it is composed of 22 aminoacids. This peptide has been compared, in different laboratory tests, with hydrocortisone and the results have demonstrated that MCDP of Apitoxinapitel has a 100-time-more powerful action as anti-inflammatory than hydrocortisone in the treatment of arthritis. (Nature, Nov, 1974). Besides, it is been described as a hypotensive blood activator. It intervenes in the potassium channels.

Adolapine: Being a neurotransmitter, it contributes to eliminate mental lacunas (“Fuzzy thinking”).

Apamine: It constitutes 2 to 3 % of Apitoxinapitel. It possesses analgesic, antigenic and anti-inflammatory properties without affecting inmunologic system.

Secapine and Tertiapine: Macromolecules with neurotransmitting properties.
Dopamine and Norepinephrine: Neurotransmitters that increase communication in the nervous system.
ENZYMES: 13 – 15 %
Phospholipase A2: It constitutes 10 to 12% of Apitoxine and it is composed of 129 aminoacids. Its main action is to hydrolyze phospholipides of cellular membrane and participate in the formation of pores in this membrane. It possesses numerous pharmacological effects: radioprotecting activity, blood hypotensor and antigenic properties among others.

Hyaluronidase: It constitutes 1 to 2% of Apitoxinapitel. Its isolation is extremely hard to obtain, so its structure is not well-known. It promotes a better circulation increasing tissue permeability and stimulating the reduction of toxic substances in a damaged area, a better penetration of the other Apitoxinapitel components and a better nutrition of these tissues. It also possesses antigenic properties and increases the inmunologic response.
Hystamine: It corresponds to almost 1% of Apitoxinapitel. It has a vasodilating action.

It also contains: Phormic Acid, Chlorhydric Acid, Orthophosphoric Acid, Choline, Triptophane, Magnesium Phosphate, and microelements such as Iron, Potassium, Iodine, Sulfur, Chlorine, Calcium, Magnesium, Manganese, Copper and Zinc. Contraindications Chronic diabetic patients (insulin consumers) Do not use in case of allergy. Pregnant women. Children under 1 tear old.


Keep out of reach of children.
External use only.
Do not use in exposed injuries, scrapings and mucosas (eyes, nose and mouth); iin case of contact, rinse with water. Only in few cases, it has been detected some sort of skin eruption that disappears after some minutes. In others, there is a slight momentary itching.
Due to the excellent blood irrigation, there have been some cases of transitory muscle rigidity, but these cases always have a faster recovery than those where this irrigation does not occur.

The action mechanism of Apitoxinapitel cream is absolutely different to that of a direct sting or bite of a bee. This cream eliminates pain, inflammation and the risk of an anaphylactic shock. It avoids infections and transmission of potential diseases provoked by the sting of a bee.

It is applied on affected zone as a fine cream layer, rubbing softly until total absorption.

Do it at least three times a day, increasing the number of applications according to needs, each time there is pain.



Keep below 30 c°, protected from sunlight.